Meningitis Research - Viral, Bacterial, Spinal, Symptoms, Treatment

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Salmonella typhimurium meningitis in an adult patient with AIDS.

Swe KS, Nagel G, Van der Westhuizen M, Hoosen AA

Department of Microbiological Pathology, Medunsa Campus, University of Limpopo, and the National Health Laboratory Services, Pretoria, South Africa.

Salmonella meningitis is an unusual complication of Salmonella sepsis and occurs mainly in children. A rare case of Salmonella typhimurium meningitis occurring in an adult HIV positive man who presented with a history of fever and diarrhoea is reported. On examination he was dehydrated, and had oral thrush, weakness of lower limbs and neck stiffness. A septic diagnostic screen was performed and he was commenced on empiric intravenous cefotaxime therapy for meningitis. S typhimurium was cultured from cerebrospinal fluid and blood culture specimens. It was non-lactose fermenting, oxidase negative, H(2)S positive and motile. Cefotaxime was continued for 14 days and the patient responded without neurological sequelae.

Published 24 December 2007 in J Clin Pathol, 61(1): 138-9.
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Meningitis Books

Handbook of Meningococcal Disease: Infection Biology, Vaccination, Clinical Management

Handbook of Meningococcal Disease: Infection Biology, Vaccination, Clinical Management