Meningitis Research Today is a free monthly online journal that collates and summarizes the latest research about Meningitis, including details on viral, bacterial, spinal, symptoms, treatment.

GeneXpert enterovirus assay: one-year experience in a routine laboratory setting and evaluation on three proficiency panels.

Seme K, Mocilnik T, Komlos KF, Doplihar A, Persing DH, Poljak M

Institute of Microbiology and Immunology, Faculty of Medicine, Zaloska 4, Ljubljana 1000, Slovenia. mario.poljak@mf.uni-lj.si.

A prospective unblinded comparative evaluation of three assays for the detection of enteroviral RNA performed on 83 positive and 79 negative cerebrospinal fluid samples showed initial and resolved sensitivities of 90.4% and 98.8%, respectively, for the Cepheid GeneXpert enterovirus assay; 94.0% and 97.6%, respectively, for the Argene enterovirus consensus kit; and 100% and 100%, respectively, for an in-house real-time PCR. The initial and resolved specificities were 100% for all three assays.

Published 4 April 2008 in J Clin Microbiol, 46(4): 1510-3.
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